As you figured out, the answer is "Yes".
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When a cheat doesn't start, the usual problem is part of the game area is blocked or off-screen. Sometimes all it takes is a single pixel off the edge of the screen or hidden behind another window to keep the cheat from working.
Another problem that crops up more and more frequently is the Zoom feature. If the browser's Zoom setting is anything other than 100%, the otter will not be able to identify the game window because it will be the wrong size.
